Random walks on binary strings applied to the somatic hypermutation of B-cells
Published in Mathematical biosciences, 2018
This paper establish a mathematical framework based on random walks on graph to introduce and evaluate the mutation mechanism at the basis of the evolutionary process leading to antibody maturation.
Recommended citation: Balelli, I., Milišić, V., Wainrib, G. (2018). Random walks on binary strings applied to the somatic hypermutation of B-cells. Mathematical biosciences, 300, 168-186.